What are collagen stimulating injections made of?

Collagen-stimulating injections are not all made from the same material. Here is what the sources say about two of them.

Calcium hydroxylapatite

Cleveland Clinic describes Radiesse as a calcium hydroxylapatite filler that stimulates collagen production to reduce fine lines and wrinkles.

PMMA beads in a collagen solution

The FDA describes one dermal filler as made with polymethylmethacrylate (PMMA) beads suspended in a solution that contains bovine (cow) collagen.

Because the makeup differs from product to product, ask your provider to name exactly what they plan to inject.

Filler safety and biostimulator choice

The FDA's guidance on dermal filler do's and don'ts for wrinkles, lips and more is a good place to start. A systematic review and meta-analysis titled Adverse Events Reported From Hyaluronic Acid Dermal Filler Injections to the Facial Region looks at reported adverse events from hyaluronic acid filler. An expert consensus on optimizing collagen biostimulator choice in LATAM covers patient selection, ethnic skin phenotypes and accessibility.

Asking what is in the syringe

Ask which product is being offered and what it is made of. Write the answer down so you can compare it with the sources above.

If the product is swapped mid-course

The answer changes when the product does. If a plan switches products during your treatment course, ask the same question again.